Method and composition for preparation of factor VIIIC
US5004804A · kind A · utility
29Cited by
4References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 12, 1984 |
| Grant date | Apr 2, 1991 |
| Priority date | — |
| Expiry date | Jan 12, 2004 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and compositions are provided for recombinant DNA production of Factor VIIIC and truncated derivatives therfeof. Based on amino acid sequences, probes are developed for isolating messenger RNA and/or chromosomal DNA encoding for Factor VIIIC. The Factor VIIIC gene in its entirety or encoding for a fragment thereof is then used for expression of Factor VIIIC in a host. The bacteriophage .lambda.FVIII23D containing the 14.43kb EcoRI fragment was deposited at the A.T.C.C. on Jan. 4, 1984 and given Accession No. 40094.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.