KS-501 derivatives
US5004833A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 15, 1989 |
| Grant date | Apr 2, 1991 |
| Priority date | — |
| Expiry date | Sep 15, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H15/203
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed are KS-501 derivatives represented by the formula (I) ##STR1## wherein X represents a hydrogen atom or COOR.sub.3, Y represents hydroxy or ##STR2## and R.sub.1, R.sub.2 and R.sub.3 are the same or different and represent a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, provided that when R.sub.1, R.sub.2 and R.sub.3 are simultaneously hydrogen atoms, and when R.sub.1, R.sub.2 and X are simultaneously hydrogen atoms, Y does not represent ##STR3## and a pharmaceutically acceptable acid addition salt thereof. The KS-501 derivatives have a platelet aggregation-inhibiting property, and are expected to be useful as antithrombotic agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.