Immunoassays for discriminating between brucellosis infections and vaccinations
US5006463A · kind A · utility
7Cited by
2References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 25, 1987 |
| Grant date | Apr 9, 1991 |
| Priority date | — |
| Expiry date | Sep 25, 2007 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/825
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method is disclosed for discriminating between cattle vaccinated against and those infected with Brucella spp. The method involves immunoassay using a purified polysaccharide containing 4,6-dideoxy-4-acylamido-D-mannopyranosyl units obtained from B. abortus or from cross-reacting organisms, and results in improved differentiation between vaccinated and infected animals. Test kits are also disclosed for performing the assay and a process is disclosed for obtaining the O-chain polysaccharides in high purity and yield.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.