Certain 7-[2,6-diisopropyl-4-phenyl-5-lower alkoxymethyl-pyrid-3-yl]-3,5-dihydroxy-6-enoates and derivatives useful for treating circulatory diseases

US5006530A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Rolf Angerbauer · Wuppertal, DE
• Peter Fey · Wuppertal, DE
• Walter Hubsch · Wuppertal, DE
• Thomas Philipps · Cologne, DE
• Hilmar Bischoff · Wuppertal, DE
• Dieter Petzinna · Mülheim an der Ruhr, DE
• Delf Schmidt · Wuppertal, DE
• Gunter Thomas · Arese, IT

Key dates

• Filing date: Jan 17, 1989
• Grant date: Apr 9, 1991
• Expiry date: Jan 17, 2009

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F7/1804
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Novel compounds for treating hyperproteinaemia, lipoproteinaemia or arteriosclerosis of the formula ##STR1## in which A, B, D and E can have varied meanings, PA1 X is --CH.sub.2 --CH.sub.2 or --CH.dbd.CH--, and PA1 R is ##STR2## wherein R.sup.21 denotes hydrogen or alkyl and PA1 R.sup.22 PA1 denotes hydrogen, PA1 denotes alkyl, aryl or aralkyl, or PA2 denotes a cation, and their oxidation products.