Substituted 3-aminosydnonimines, processes for their preparation and their use

US5006540A · kind A · utility

Assignee

• Cassella Aktiengesellschaft · DE

Inventors

• Karl Schonafinger · Alzenau, DE
• Rudi Beyerle · Frankfurt, DE
• Melitta Just · Langen, DE
• Helmut Bohn · Schöneck, DE
• Jorg Ostrowski · Rodenbach, DE

Key dates

• Filing date: Oct 17, 1989
• Grant date: Apr 9, 1991
• Expiry date: Oct 17, 2009

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P9/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Substituted 3-aminosydnonimines of the formula I ##STR1## and their pharmacologically acceptable acid addition salts, wherein R.sup.1 denotes, for example, alkyl having 1 to 8 C atoms, R.sup.2 denotes hydrogen or the radical --COR.sup.3 and R.sup.3 denotes, for example, an aliphatic radical having 1 to 4 C atoms, are prepared, for example, by cyclization of a compound of the formula II ##STR2## and if appropriate subsequent acylation and have useful pharmacological properties.