Arylthioalkylphenyl carboxylic acids, derivatives thereof, compositions containing same and method of use
US5006542A · kind A · utility
16Cited by
5References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 31, 1988 |
| Grant date | Apr 9, 1991 |
| Priority date | — |
| Expiry date | Oct 31, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C317/18
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Arylthioalkylphenylcarboxylic acids are provided which have the structure ##STR1## wherein Ar represents an aryl group including phenyl or naphthyl which may or may not include one or more substituents, X is COOR where R is hydrogen, alkali metal, or lower alkyl, or X is 5-tetrazolyl or ##STR2## where R.sup.1 is lower alkyl or aryl, p is 1 to 5, and m is 1 to 4. These compounds are cardiovascular agents which exhibit thromboxane antagonist activity and thus are useful in the treatment of thrombotic and vasopastic diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.