Methylated cyclodextrin type compounds and process for preparing same
US5008386A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 12, 1988 |
| Grant date | Apr 16, 1991 |
| Priority date | — |
| Expiry date | Oct 12, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08B37/0012
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to novel partially methylated carboxyacyl-cyclodextrins of the general formula (I), ##STR1## wherein A means the cyclodextrin skeleton of the general formula (II) ##STR2## containing the substituents in the position labelled by the wavy line; W stands for an alkylene, alkenylene or arylene group or the substituted derivatives thereof; PA1 R means hydrogen, an alkyl, aryl or aralkyl group; PA1 m is 6, 7 or 8; PA1 n is an integer from 1 to 2m; and PA1 p is 2m-n+z, wherein the value of z is from 0 to 3 as well as their salts. The novel derivatives induce less haemolytic effect than the cyclodextrin compounds used as starting materials.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.