Reagent and method for determining activity of retroviral protease
US5011910A · kind A · utility
37Cited by
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2Claims
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Key dates
| Filing date | Dec 28, 1989 |
| Grant date | Apr 30, 1991 |
| Priority date | — |
| Expiry date | Dec 28, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16222
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Novel fluorogenic substrates for retroviral protease, e.g. HIV protease, having the chemical structure X--Thr--Ile--Nle--Phe(Y)--Gln--Arg--NH.sub.2 wherein X is a fluorogenic group and Y is an acceptor for the fluorogenic group, and their use in a fluorometric method for the determination of retroviral protease is disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.