Novel (trans 1-propenyl)disulfide derivative and process for preparing the same
US5011975A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 17, 1989 |
| Grant date | Apr 30, 1991 |
| Priority date | — |
| Expiry date | Jul 17, 2009 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A (trans 1-propenyl)disulfide derivative having a distinguished anti-tumor effect, represented by the following general formula: ##STR1## , wherein R is a lower alkylene group and R' is a hydrogen atom or a carboxyl protective group, is prepared by allowing a carboxylic acid thiol derivative, represented by the following general formula: EQU AS--R--COOR' , wherein R and R' have the same meanings as defined above and A is a thiol protective group releasable by a halogenating agent, to react with a trans 1-propenethiol derivative represented by the following general formula: ##STR2## , wherein A has the same meanings as defined above, in the presence of a halogenating agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.