New thymopentin retro-inverso analogs and fragments thereof, a process of preparation of the new compounds and the intermediates obtained therein
US5013723A · kind A · utility
8Cited by
3References
5Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Mar 15, 1988 |
| Grant date | May 7, 1991 |
| Priority date | — |
| Expiry date | Mar 15, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
New retro-inverso analogs of thymopentin (TP5) and of its tripeptide fragment (TP5.sup.1-3) of general formula (I) ##STR1## are described wherein R is hydrogen or an acyl radical, and R.sup.1 is --OR.sup.2 or ##STR2## wherein R.sup.2 is hydrogen or a hydrocarbyl radical, and the corresponding pharmaceutically acceptable acid- or base-addition salts. The new compounds are enzyme-resistant immunomodulatory peptides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.