Magnetically modulated polymeric drug release system
US5019372A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 7, 1990 |
| Grant date | May 28, 1991 |
| Priority date | — |
| Expiry date | Sep 7, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/5094
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A magnetically responsive composition for the modulated, sustained administration of a biologically active substance, the composition being in the form of a body sized and shaped for placement in the environment of use, the environment including an aqueous fluid, the body comprising, in admixture, a first phase comprising a biocompatible, plastically deformable, polymeric matrix, the polymeric matrix being insoluble in the environment of use, a second phase having a biologically active substance distributed throughout the matrix to be released to the aqueous fluid outside the matrix, and a third phase comprising a magnetically responsive substance encapsulated within the matrix so that, upon exposure of the body to an oscillating magnetic field, the rate of release of the biologically active substance to the aqueous fluid is increased.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.