Immunonodulating compositions and their use
US5019384A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 13, 1989 |
| Grant date | May 28, 1991 |
| Priority date | — |
| Expiry date | Nov 13, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/16034
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel methods or compositions are provided for modulating the immune system, so as to be able to selectively stimulate or inactivate lymphocytes in relation to a particular transplantation antigen content. Particularly, mixtures may be employed associated with the more common transplanatation antigens of a host population. In this manner, a large number of people can be treated, for example, by immunization, stimulation of particular T-cells or B-cells in relation to a pathogenic invasion of other aberrant state, e.g. neoplasia, treatment of autoimmune diseases, and the like. Particularly, the compositions may involve an oligopeptide involving as a first region a consensus sequence and an epitope or the first region may be joined to a second region comprising an antibody target sequence which is capable of competing with an epitopic site of an antigen of interest.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.