2-substituted N,N'-ditrimethoxybenzoyl piperazines and therapeutic compositions containing them

US5019576A · kind A · utility

Assignee

• Société de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S) SAS · FR

Inventors

• Pierre Braquet · Garches, FR
• Eduardo Pirotzky · Paris, FR
• Jean-Jacques Godfroid · Paris, FR
• Francoise Heymans · Paris, FR

Key dates

• Filing date: Apr 9, 1990
• Grant date: May 28, 1991
• Expiry date: Apr 9, 2010

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D241/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to piperazine derivatives of the general formula I ##STR1## wherein --(CH.sub.2).sub.n -- represents a straight or branched chain alkyl group having from n=1 to n=20 carbon atoms, and R represents a hydrogen atom, a branched alkyl group, a cycloalkyl group having from 5 to 10 carbon atoms, a phenyl group, optionally substituted by one or several chlorine atoms, methyl or methoxy groups, or straight or branched chain alkenyl groups having from 3 to 11 carbon atoms, to a preparation process of said compounds and to therapeutic compositions containing them as an active ingredient.