Method and composition for treating hyperproliferative skin diseases using 6-aminopurine cytokinins
US5021422A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 8, 1989 |
| Grant date | Jun 4, 1991 |
| Priority date | — |
| Expiry date | Jun 8, 2009 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
It has been discovered that 6-(substituted amino)purine cytokinins, such as kinetin, induce differentiation, and consequently reduce or eliminate the abnormally high rate of proliferation, of hyperproliferating cells associated with hyperproliferative skin diseases, such as psoriasis. Thus, the present invention provides methods and compositions for treating hyperproliferative skin diseases in mammals, particularly such diseases associated with hyperproliferating epidermal cells in humans, by administering to the hyperproliferating cells associated with such a disease, in the skin of a mammal suffering therefrom, a differentiation-inducing effective amount of a 6-(substituted amino)purine cytokinin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.