Avermectin derivatives
US5023241A · kind A · utility
12Cited by
6References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 31, 1989 |
| Grant date | Jun 11, 1991 |
| Priority date | — |
| Expiry date | Jul 31, 2009 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P33/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel avermectin derivatives are disclosed, wherein the 4"-hydroxy group is replaced by a substituted acylamino or benzoylamino group. These avermectin derivatives can be further derivatized at the 5- and 23-positions as ketoximes or O-substituted ketoximes. The 4"-substituted avermectin derivatives are prepared by the acylation of the known 4"-aminoavermectins with acylating reagents. The new compounds are potent anti-parasitic agents, in particular, the compounds are anthelmintic, insecticidal and acaricidal agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.