Substituted uracils, processes for their preparation and their use against parasitic protozoa

US5023260A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Werner Lindner · Eppstein, DE
• Axel Haberkorn · Wuppertal, DE

Key dates

• Filing date: Mar 22, 1990
• Grant date: Jun 11, 1991
• Expiry date: Mar 22, 2010

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D239/557
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A substituted uracil useful for combating parasitic protozoa of the formula ##STR1## in which R.sup.1 represents a carbocyclic aromatic or heteroaromatic radical, which are optionally substituted, PA0 R.sup.2 represents H; or alkyl, alkenyl, alkinyl or aralkyl, each of which are optionally substituted, PA0 R.sup.3 represents one or more identical or different hydrogen, halogen, alkyl, halogenoalkyl, alkoxy, alkylthio, halogenoalkoxy, halogenoalkylthio, cyano, alkoxycarbonyl, alkylsulphonyl or halogenoalkylsulphonyl radicals, PA0 R.sup.4 represents hydrogen; or a straight-chain, branched or cyclic alkyl, alkenyl, alkinyl or aralkyl, each of which are optionally substituted.