Pharmaceutical microemulsions
US5023271A · kind A · utility
50Cited by
5References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 13, 1985 |
| Grant date | Jun 11, 1991 |
| Priority date | — |
| Expiry date | Aug 13, 2005 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1075
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for parenteral administration of fat-soluble pharmaceuticals and vitamins using microemulsions is disclosed. The microemulsions are comprised of a naturally occurring amphipatic substance and a hydrophobic lipid along with the active ingredient, are size selected for 300-1000 .ANG. pseudomicelles, and permit safe intravenous injection of the active ingredient. Levels of the active ingredient in the various lipoprotein fractions of serum appear to mimic the natural distribution of the administered drug if taken orally.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.