Nucleic acids encoding the delta chain of the T cell antigen receptor
US5024940A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Oct 29, 1987 |
| Grant date | Jun 18, 1991 |
| Priority date | — |
| Expiry date | Oct 29, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K16/2809
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides purified polypeptides which comprises at least a portion of a a .delta.T cell receptor polypeptide, a .gamma.T cell receptor polypeptide, a .gamma..delta.T cell receptor complex or a .gamma..delta.T cell receptor complex. Substances capable of forming complexes with these polypeptides are also provided. Additonally, methods for detecting T cells which have within them or on their surfaces a polypeptide of the present invention are provided. Moreover, methods for diagnosing immune system abnormalities are provided which comprise measuring in a sample from a subject the number of T cells which have within them or on their surfaces a polypeptide of the present invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.