Pyrimidine-thioalkyl pyridine derivatives, medicaments containing these compounds, and method of treatment

US5025016A · kind A · utility

Assignee

• Ludwig Heumann & Co. GmbH · DE

Inventors

• Kurt H. Ahrens · Nürnberg, DE
• Helmut Schickaneder · Eckental, DE
• Heidrun Engler · Cadolzburg, DE
• Istvan Szeleny · Arnstorf, DE

Key dates

• Filing date: Sep 26, 1988
• Grant date: Jun 18, 1991
• Expiry date: Sep 26, 2008

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P29/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to pyrimidine-thioalkyl pyridine derivatives corresponding to the following general formula ##STR1## in which R.sub.1 to R.sub.4, independently of one another, represent hydrogen, lower alkyl, halogen, amino or hydroxy groups, R.sub.5 represents a free electron pair or a lower alkyl group, a halogen atom, m has the value 0 or 1, the pyrimidine-thioalkyl group being bonded in the 2-, 3- or 4-position of the pyridine ring, and to therapeutically compatible acid addition salts thereof. The invention also relates to a process for producing the new pyrimidine-thioalkyl pyridine derivatives and to medicaments containing these compounds.