Methods for imaging atherosclerotic plaque
US5026537A · kind A · utility
54Cited by
7References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 6, 1989 |
| Grant date | Jun 25, 1991 |
| Priority date | — |
| Expiry date | Apr 6, 2009 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/866
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention pertains to a method of imaging atherosclerotic plaque using radiolabeled monoclonal antibodies that are specific for activated platelets or activated endothelial cells. The method is capable of determining the site of endothelial injury. This method involves the administration of a platelet-specific labeled monoclonal antibody or antibody fragment to a patient. The antibody is allowed to accumulate at the plaque site and the plaque is then scanned with a photoscanner. The detected signals are then converted into an image of the plaque.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.