Fermentation process for the preparation of novel C.25 (substituted(2-propenyl) milbemycins
US5026643A · kind A · utility
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2Claims
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Key dates
| Filing date | Feb 26, 1990 |
| Grant date | Jun 25, 1991 |
| Priority date | — |
| Expiry date | Feb 26, 2010 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/886
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Antiparasitic milbemycin derivatives having at the C.25 position a substituted 2-propenyl group --C(CH.sub.3).dbd.CH--R.sup.2 wherein R.sup.2 is a C.sub.3 -C.sub.8 alkyl, alkenyl or alkynyl group which may optionally contain an oxygen or sulphur atom as part of the chain, or a C.sub.3 -C.sub.8 cycloalkyl or cycloalkenyl group, or a 3 to 6 membered oxygen or sulphur containing heterocyclic ring which may optionally be substituted by one or more alkyl groups or halogen atoms; and process for their preparation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.