Morpholines and morpholine-N-oxides and pharmaceutical compositions containing these compounds

US5026702A · kind A · utility

Assignee

• Dr. Karl Thomae GmbH · DE

Inventors

• Manfred Reiffen · Biberach, DE
• Michael Mark · Biberach an der Riß, DE
• Robert Sauter · Biberach, DE
• Wolfgang Grell · Biberach, DE

Key dates

• Filing date: Mar 23, 1989
• Grant date: Jun 25, 1991
• Expiry date: Mar 23, 2009

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to new morpholines and morpholine-N-oxides of formula ##STR1## wherein the substituents are defined hereunder, which compounds have valuable pharmacological properties, namely an effect on the metabolism, preferably the effect of lowering blood sugar and reducing body fat, and the effect of lowering the atherogenic .beta.-lipoproteins VLDL and LDL, and a performance enhancing effect in animals.