Compounds with bronchodilator activity
US5026724A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 5, 1989 |
| Grant date | Jun 25, 1991 |
| Priority date | — |
| Expiry date | Jul 5, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D307/85
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method is provided for treating patients suffering from or susceptible to bronchoconstriction, particularly for patients suffering from an asthmatic attach which comprises the use of benzothiophene, benzofuran, dihydronaphthalene or indene derivatives represented by formula I ##STR1## wherein each of R.sup.1, R.sup.2, R.sup.3 and R.sup.4 is independently H, (1-4C) alkyl, (1-4C) halogen substituted alkyl, OH, (1-4C) alkoxy, (1-4C) halogen substituted alkoxy, NO.sub.2, CN, halogen, an unsubstituted or (1-4C) alkyl substituted amino group, or wherein two adjacent groups R.sup.1, R.sup.2, R.sup.3 or R.sup.4 together form methylenedioxy; PA0 X is S, O or (CH.sub.2).sub.m in which m is 1 or 2; PA0 R.sup.5 is H or (1-4C) alkyl; PA0 R.sup.6 is H, NH.sub.2 or (1-4C) alkyl; PA0 R.sup.7 is H, (1-4C) alkyl or OR.sup.8 in which PA0 R.sup.8 is H, (1-4C) alkyl or (1-8C) acyl; PA0 and its pharmaceutically acceptable salts for the preparation of a medicament with bronchodilator activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.