Stereospecific process for the preparation of furo[3,4-c]pyridine, enantiomer, compounds thus obtained and therapeutical compositions thereof
US5026855A · kind A · utility
2Cited by
8References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 28, 1989 |
| Grant date | Jun 25, 1991 |
| Priority date | — |
| Expiry date | Nov 28, 2009 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P9/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to stereospecific processes for the preparation of enantiomers of 3-substituted-furo[3,4-c]pyridine of formula I, wherein R.sub.3, R.sub.4 and R.sub.6 stand for various substituents, comprising the steps of: oxidation of a racemic pyridine derivative of formula II, reduction of the resulting ketone with a reducing agent, sterospecific locking or blocking of the OH group of the enantiomer alcohol, opening of the acetonide ring and cyclization of the resulting compound. ##STR1## The present invention also relates to compounds thus obtained and therapeutical compositions thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.