Preparation of 2-acyl-6-methylnaphthalenes
US5026917A · kind A · utility
1Cited by
4References
50Claims
0Family size
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Inventors
Key dates
| Filing date | Mar 1, 1990 |
| Grant date | Jun 25, 1991 |
| Priority date | — |
| Expiry date | Mar 1, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C45/81
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A regioselective acetylation process is provided for converting a 2-methylnaphthalene compound to a 2-acetyl-6-methylnaphthalene compound. The process is conducted under liquid phase conditions using a new complexing agent which is regiospecific for the beta position of naphthalene and which is an electron-rich, carbon-based compound. A preferred such agent is hexamethylbenzene. Also provided is a novel method for producing a 2-acetyl-6-methylnaphthalene compound of relative high purity from isomer mixtures by recrystallization from a hydrocarbon solvent, such as n-octane, isooctane, or n-nonane.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.