System and method for transdermal drug delivery
US5028435A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 22, 1989 |
| Grant date | Jul 2, 1991 |
| Priority date | — |
| Expiry date | May 22, 2009 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/7023
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Transdermal drug delivery systems comprise a backing or enclosure having a matrix layer which incorporates a drug and a percutaneous enhancer for the drug. The percutaneous enhancer and/or drug will be contained within polymeric particles dispersed through the matrix layer, where the polymeric particles define pore networks which are sized to release the enhancer and/or drug into the matrix layer at rate(s) selected to provide for a desired rate of drug penetration. By isolating the enhancer within the polymeric particles, adverse interactions between the enhancer and the matrix layer and/or the drug can be minimized. Moreover, the release rate of the enhancer into the matrix layer can be carefully controlled, which in turn controls the penetration rate of the drug into the treated host.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.