Blood substitutes
US5028588A · kind A · utility
126Cited by
1References
28Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 16, 1988 |
| Grant date | Jul 2, 1991 |
| Priority date | — |
| Expiry date | May 16, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Solutions of mutant hemoglobins having a lower oxygen affinity than that of native hemoglobin are used as blood substitutes. The mutant hemoglobins are preferably obtained by recombinant DNA techniques. Both alpha and beta globin chains can now be so prepared, making possible the production of wholly artificial hemoglobin, whether conventional or mutant in form. Solutions of wholly artificial hemoglobins are also used as blood substitutes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.