Heteroarylethanol-pyridylalkylamines for controlling animal growth

US5028617A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Hans Lindel · Leverkusen, DE
• Werner Hallenbach · Nordhorn, DE
• Friedrich Berschauer · Wuppertal, DE
• Heinrich A. Greife · Langenfeld, DE
• Gernot Klotz · Leichlingen, DE

Key dates

• Filing date: Jan 19, 1990
• Grant date: Jul 2, 1991
• Expiry date: Jan 19, 2010

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D213/80
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A compound for promoting livestock production and for controlling obesity in humans and animals, of the formula ##STR1## in which A represents .dbd.CH-- or .dbd.N--, PA1 R.sup.0 represents hydrogen or methyl, PA1 R.sup.1 and R.sup.3 each independently represents hydrogen, hydroxyl, halogen, cyano, alkyl, halogenoalkyl, hydroxyalkyl, alkoxycarbonyl, aminocarbonyl, mono- and dialkylaminocarbonyl, alkoxy, halogenoalkoxy, halogenoalkylthio, NHSO.sub.2 -alkyl, PA1 R.sup.2 represents hydrogen, hydroxyl, alkoxy or the radical --NR.sup.5 R.sup.6, PA1 R.sup.4 represents hydrogen, C.sub.1 -C.sub.10 -alkyl which is optionally substituted by hydroxyl, halogen, alkoxy, acyloxy or the radical --NH.sup.7 R.sup.8, or represents the radical COR.sup.9 or the radical --O--Z--R.sup.10, PA1 Z represents C.sub.1 -C.sub.10 -alkylene, -alkenylene or alkynylene, PA1 R.sup.5 represents hydrogen or alkyl, PA1 R.sup.6 represents hydrogen, alkyl, halogenoalkyl or acyl, or R.sup.5 and R.sup.6 together with the adjoining N atom form a saturated or unsaturated heterocyclic 4-, 5- or 6-membered ring, PA1 R.sup.7 and R.sup.8 each independently represents hydrogen, optionally substituted alkyl, optionally substitute…