Process for the manufacture of collagen membranes used for hemostasis, the dressing of wounds and for implants

US5028695A · kind A · utility

Assignee

• Chemokol Gesellschaft Zur Entwicklung von Kollagenprodukten · DE

Inventors

• Zdenek Eckmayer · Weinheim, DE
• Ernst Janzen · Laren, NL
• Gunter Ruttgers · Stolberg, DE

Key dates

• Filing date: Mar 10, 1989
• Grant date: Jul 2, 1991
• Expiry date: Mar 10, 2009

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61F2310/00365
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

The invention concerns a process for the manufacture of collagen membranes for medical applications, in which process the collagen raw materials obtained from cattle or pig collagen are mechanically freed of fatty residues and treated with diluted alkali and acids and, if need be, enzymes. It is thoroughly washed between these steps to thus clean the collagen raw material eliminating the accompanying contamination. It is then processed further while obtaining a collagen matrix with a dry weight of approximately 25% by weight. Thus obtained are collagen membranes, in which the original integral cohesion remains and with which a fast hemostatic effect is achieved; said membranes are also extremely flexible and they adhere well to the surface of a wound.