Process for the preparation of derivatives of sulfonyl indolizine and their use as synthetic intermediates
US5028710A · kind A · utility
1Cited by
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8Claims
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Assignee
Inventors
Key dates
| Filing date | Jun 8, 1990 |
| Grant date | Jul 2, 1991 |
| Priority date | — |
| Expiry date | Jun 8, 2010 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The object of the invention is a process for the preparation of derivatives of 3-sulfonyl indolizine of general formula: ##STR1## in which: R is selected from hydrogen, alkyl, cycloalkyl, substituted or unsubstituted phenyl, PA1 R.sub.1 is a protecting group for hydroxyl, PA1 R.sub.2 and R.sub.3, identical or different, is each selected from hydrogen, methyl or ethyl or halogen. These compounds are intermediates which can be used for the preparation of 3-aminoalkoxyphenylsulfonyl-indolizines, which are useful in the treatment of certain diseases of the cardiovascular system.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.