Bioerodible polymers useful for the controlled release of therapeutic agents
US5030457A · kind A · utility
28Cited by
6References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 28, 1989 |
| Grant date | Jul 9, 1991 |
| Priority date | — |
| Expiry date | Aug 28, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G65/34
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Bioerodible ortho ester polymers useful for preparing soft form bioerodible pharmaceutical compositions such as ointments, creams, gels and the like are provided. A novel synthetic method for preparing the polymers is provided as well. Synthesis involves a one-step reaction between a monomeric ortho ester and a triol. The pharmaceutical compositions of the invention are useful for the controlled release of therapeutic agents, and may be administered for a variety of purposes, such as for the treatment of deep wounds, including burns, and for the treatment of periodontal disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.