Methods and compositions for the identification of metastatic human tumors
US5030559A · kind A · utility
11Cited by
5References
29Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 1, 1986 |
| Grant date | Jul 9, 1991 |
| Priority date | — |
| Expiry date | Apr 1, 2006 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/828
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are monoclonal antibodies which react with human tumor cells, particularly metastatic human tumor cells, but not with normal human tissues tested. The monoclonal antibodies are prepared against a 580 kilodalton glycoprotein antigen, designated gp580, which is isolated from either rat or human tumor cells. Methods for isolating the glycoprotein antigen are disclosed as well. Moreover, techniques are disclosed for utilizing these antibodies both in the detection and in the prevention of human tumor lesions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.