Gene transfer using transformed, neodetermined, embryonic cells
US5032407A · kind A · utility
22Cited by
1References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 16, 1987 |
| Grant date | Jul 16, 1991 |
| Priority date | — |
| Expiry date | Jan 16, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention is directed to a method for the preparation of carrier cells capable of delivering exogenous genetic material to a particular tissue of the body by means of embryonic cells competent to develop into that tissue, and essentially only that tissue, said cells bearing the exogenous genetic material. The preferred carrier cells are mesodermal cells of the yolk sac or embryonic forebrain or midbrain cells, and the desired genetic material is preferably introduced into the cells by in vitro transformation with an amphotrophic retroviral vector.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.