Method for expression and secretion in bacillus
US5032510A · kind A · utility
35Cited by
1References
43Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 17, 1988 |
| Grant date | Jul 16, 1991 |
| Priority date | — |
| Expiry date | Jun 17, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/75
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention discloses a novel method for expressing and secreting a functional polypeptide in Bacillus including the vectors and transformants for the practice thereof. The vectors comprise the transcriptional and translational activity sequence, and optionally the signal peptide coding sequence, of the Staphylococcus aureus nuclease gene. The vectors and transformants are useful for the production and secretion of human hormones such as human proinsulin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.