Method for producing secretable glycosyltransferases and other Golgi processing enzymes
US5032519A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 24, 1989 |
| Grant date | Jul 16, 1991 |
| Priority date | — |
| Expiry date | Oct 24, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P19/26
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method for genetically engineering cells to produce soluble and secretable Golgi processing enzymes instead of naturally occurring membrane-bound enzymes. Cells are genetically engineered to express glycosyltransferases which lack both a membrane anchor and a r This invention was made with government support under Grant Contract Nos. GM-27904 and GM-11557 awarded by the National Institute of Health. The government has certain rights in this invention. The publications and other reference materials referred to herein to describe the background of the invention and to provide additional detail regarding its practice are hereby incorporated by reference. For convenience, the reference materials are numerically referenced and grouped in the appended bibliography.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.