Homologs of aprotinin produced from a recombinant host, process, expression vector and recombinant host therefor and pharmaceutical use thereof

US5032573A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Ernst-August Auerswald · Munich, DE
• Werner Schroder · Wuppertal, DE
• Eugen Schnabel · Wuppertal, DE
• Wolfgang Bruns · Wuppertal, DE
• Gerd Reinhardt · Kelkheim, DE
• Michael P. Kotick · Elkhart, US

Key dates

• Filing date: Oct 2, 1989
• Grant date: Jul 16, 1991
• Expiry date: Oct 2, 2009

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Microbially produced aprotinin and aprotinin homologs used for treating patients suffering from an excess release of pancreatic elastase, serum elastase or leukocyte elastase.