Patent · US Expired

Novel antimicrobial peptide

US5032574A · kind A · utility

18Cited by
1References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 26, 1988
Grant dateJul 16, 1991
Priority date
Expiry dateMay 26, 2008

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

This invention provides a purified polypeptide useful as an antimicrobial agent. This purified polypeptide has been derived from human granulocytes, and has a molecular weight of about 3,700 daltons and the N-terminal amino acid sequence val-cys-ser-cys-arg-leu-val-phe-cys-arg-arg-thr-glu- leu-arg-val-gly-asn-cys-leu-ile-gly-gly-val-ser-phe-thr-try-cys-thr-arg-va l. This invention also provides methods for producing this polypeptide, pharmaceutical compositions containing the polypeptide, and uses thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.