Amine rich fluorinated polyurethaneureas and their use in a method to immobilize an antithrombogenic agent on a device surface
US5032666A · kind A · utility
81Cited by
4References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 19, 1989 |
| Grant date | Jul 16, 1991 |
| Priority date | — |
| Expiry date | Jun 19, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G18/12
- WIPO fieldMacromolecular chemistry, polymers
- WIPO sectorChemistry
Abstract
A thermoplastic polyurethaneurea having free amino groups is the reaction product of a diisocyanate, a fluorinated polyol, a non-fluorinated polyol and a polyamine. The invention includes a shaped polymeric support structure having the thermoplastic polyurethaneurea coated thereon and a medical article comprising the coated support and heparin covalently bonded to the free amino groups of the coated support. In another aspect of the invention, a method for preparing the heparinized medical article is provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.