Plasma gas discharge treatment for improving the compatibility of biomaterials
US5034265A · kind A · utility
73Cited by
17References
10Claims
0Family size
Assignee
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Key dates
| Filing date | Aug 21, 1989 |
| Grant date | Jul 23, 1991 |
| Priority date | — |
| Expiry date | Aug 21, 2009 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T442/2549
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method of treating articles to improve their biocompatibility is disclosed. A polymeric substrate material is positioned within a reactor vessel and exposed to plasma gas discharge in the presence of an atmosphere of an inert gas and then in the presence of an organic gas, such as a fluorinated hydrocarbon gas, which forms a thin, biocompatible surface covalently bonded to the surface of the substrate. The method is particularly useful in the treatment of vascular graft materials to produce grafts that are both thrombi- and emboli-resistant.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.