Patent · US Expired

Stable, water soluble salt compositions of M-AMSA in 1-methyl-2-pyrrolidinone

US5034397A · kind A · utility

5Cited by
2References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 12, 1985
Grant dateJul 23, 1991
Priority date
Expiry dateDec 12, 2005

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K47/22
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

This invention relates to novel compositions of the antitumor agent [4'-9-(acridinylamino) methanesulfon-m-anisidide], (m-AMSA). Acid salts of m-AMSA are dissolved in 1-methyl-2-pyrrolidinone to provide highly stable solutions. The solutions may be diluted with Sterile Water for Injection, U.S.P. to provide stable, non-precipitating solutions for intravenous use.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.