Patent · US Expired

Non-ionic contrast media from ionic contrast media

US5035877A · kind A · utility

0Cited by

13References

1Claims

0Family size

Assignee

Cook Imaging Corporation · US

Inventors

Milos Sovak · Village of La Jolla, US
Ramachandran Ranganathan · Princeton, US

Key dates

Filing date	Sep 14, 1990
Grant date	Jul 30, 1991
Priority date	—
Expiry date	Sep 14, 2010

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C233/16
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Novel non-ionic contrast media are efficiently prepared from generally available ionic contrast media. Particularly, polyhydroxyhalohydrocarbons are employed with a triiodo-substituted acylamido benzoic acids in aqueous weakly basic media to selectively substitute the amido nitrogen, followed by activation of the carboxyl group for amide formation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.