Anthelmintic active compound combinations

US5036069A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Peter Andrews · Wuppertal, DE
• Hubert Dorn · Wuppertal, DE
• Herbert Voege · Leverkusen, DE

Key dates

• Filing date: Oct 12, 1989
• Grant date: Jul 30, 1991
• Expiry date: Oct 12, 2009

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

An anthelminthic composition comprising a mixture of phenyl-guanidines of the formula ##STR1## in which R.sup.1 represents hydrogen, optionally substituted alkyl, cycloalkyl, alkoxy, aryl or amino, PA1 R.sup.2 represents hydrogen, optionally substituted alkyl, cycloalkyl, alkenyl, alkinyl, aryl, alkoxy or alkenoxy, PA1 R.sup.3 represents hydrogen, optionally substituted alkyl, cycloalkyl, alkenyl, alkinyl or aryl, PA1 R.sup.4 represents alkyl, alkoxy, phenoxy, alkylthio, phenylthio, phenylsulphinyl, phenylsulphonyl or benzoly which are in each case optionally substituted hy halogen, alkoxy, alkylthio, halogenoalkoxy or halogenoalkylthio, or benzimidazoles of the formula ##STR2## R.sup.3 and R.sup.4 have the meaning specified above together with tetrahydropyrimidines of the formula ##STR3## in which R.sup.5 represents hydrogen or alkyl, R.sup.6 represents optionally substituted phenyl or thienyl, and X represents --(CH.sub.2).sub.2-3 -- or --CH.dbd.CH--.