Derivatives of (AZA) naphthalensultam, their preparation and compositions containing them
US5036075A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 6, 1990 |
| Grant date | Jul 30, 1991 |
| Priority date | — |
| Expiry date | Nov 6, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D513/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to a compound of the formula: ##STR1## in which R.sub.1 represents PA1 a 1,2,3,6-tetrahydro-1-pyridyl radical substituted in the 4-position. PA1 a 1-piperazinyl radical substituted in the 4-position. PA1 a piperidino radical substituted in the 4-position either: PA0 R.sub.2 and R.sub.3, which are identical, represent a hydrogen or halogen atom and R.sub.4 represents a hydrogen atom or PA0 R.sub.2 and R.sub.4 represent a hydrogen atom and R.sub.3 represents a halogen atom or an acetylamino radical or PA0 R.sub.2 and R.sub.3 represent a hydrogen atom and R.sub.4 represents a halogen atom and R.sub.5 represents a --CH.dbd. group. PA0 or R.sub.2, R.sub.3 and R.sub.4 represent a hydrogen atom and R.sub.5 represents a nitrogen atom. PA0 R.sub.6 represents an alkylene chain containing 2 to 4 carbon atoms or a propylene chain substituted in the 1- or 3-position by an alkyl radical or in the 2-position by an alkyl, alkoxy, hydroxy, dialkylamino, piperidino, morpholino or thiomorpholino radical, and their salts, are useful in therapy for their ability to block serotonin receptors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.