Preparation of 2,5-diazabicyclo[2.2.1]heptanes and intermediates
US5036153A · kind A · utility
7Cited by
5References
2Claims
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Inventors
Key dates
| Filing date | Oct 18, 1989 |
| Grant date | Jul 30, 1991 |
| Priority date | — |
| Expiry date | Oct 18, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D207/48
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
(R,R)-2,5-Diazabicyclo[ 2.2.1]heptanes are prepared from a compound of the formula ##STR1## wherein X and R.sub.2 are as defined herein, by heating with tosylchloride in pyridine, reacting the formed compound of the formula ##STR2## with a C.sub.1 -C.sub.6 alkylamine or ammonia, and reducing or hydrolyzing the formed compound of the formula ##STR3## wherein R.sub.1 is hydrogen or C.sub.1 -C.sub.6 alkyl.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.