Patent · US Expired

Method of treating tissue damaged by reperfusion injury

US5041288A · kind A · utility

38Cited by
23References
9Claims
0Family size

Assignee

Inventor

Key dates

Filing dateMay 4, 1990
Grant dateAug 20, 1991
Priority date
Expiry dateMay 4, 2010

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/49
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides a method for treating tissue damaged by reperfusion injury. The method includes injecting an effective amount of a surface-active copolymer into the human or animal with the tissue damaged by reperfusion injury an effective amount of a surface-active copolymer. The surface-active copolymer can be an ethylene oxide-propylene oxide condensation product with the following general formula: EQU HO(C.sub.2 H.sub.4 O).sub.b (C.sub.3 H.sub.6 O).sub.a (C.sub.2 H.sub.4 O).sub.b H wherein a is an integer such that the hydrophobe represented by (C.sub.3 H.sub.6 O) has a molecular weight of approximately 950 to 4000, preferably approximately 1200 to 3500, and b is an integer such that the hydrophile portion represented by (C.sub.2 H.sub.4 O) constitutes approximately 50% to 90% by weight of the compound.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.