Patent · US Expired

3-[1-thiazolidinylbutyl-4-piperazinyl]-1H-indazoles

US5041445A · kind A · utility

5Cited by
4References
22Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 21, 1990
Grant dateAug 20, 1991
Priority date
Expiry dateMay 21, 2010

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P25/18
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

This invention relates to 3-[1-thiazolidinylbutyl-4-piperazinyl]-1H-indazoles of the formula ##STR1## where R.sub.1 and R.sub.2 are each independently hydrogen or loweralkyl or R.sub.1 and R.sub.2 taken together with the carbon atom to which they are attached form a cyclopentane, cyclohexane or cycloheptane ring; R.sub.3 and R.sub.4 are independently hydrogen or loweralkyl or R.sub.3 and R.sub.4 taken together with the carbon atom to which they are attached form a cyclopentane, cyclohexane or cycloheptane ring; R.sub.5 is hydrogen, loweralkyl, alkanoyl or aroyl; X is hydrogen, halogen, loweralkyl or alkoxy; m is an integer of 1 to 3, the pharmaceutically acceptable acid addition salts thereof and where applicable, the optical, geometrical and stereoisomers and racemic mixtures thereof. The compounds of this invention are useful as antipsychotic agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.