Patent · US Expired

Antileukemic and immunostimulant peptides

US5041535A · kind A · utility

4Cited by

2References

3Claims

0Family size

Assignee

Richter Gedeon Vegyeszeti Gyar RT · HU

Inventors

Olga Nyeki nee Kuprina · Budapest, HU
Istvan Schon · Budapest, HU
Lajos Kisfaludy · Budapest, HU
Laszlo Denes · Budapest, HU
Gyorgy Hajos · Budapest, HU
Laszlo Szporny · Budapest, HU
Bela Szende · Budapest, HU
Karoly Lapis · Budapest, HU

Key dates

Filing date	Nov 20, 1987
Grant date	Aug 20, 1991
Priority date	—
Expiry date	Nov 20, 2007

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The new peptides of the Formulae PA0 (1) Glp-Lys-NH.sub.2 PA0 (2) Glp-Glu-Lys-NH.sub.2 PA0 (3) Arg-Lys-Glu-NH.sub.2 PA0 (4) Arg-lys-Asp-NH.sub.2 PA0 (5) Arg-Lys-Glu-OH PA0 (6) Arg-Lys-Gln-OH PA0 (7) Leu-Val-Ala-OH PA0 (8) Arg-Orn-Asp-Val-NH.sub.2 PA0 (9) Arg-Orn-Asp-Val-OH PA0 (10) Lys-Glu-Lys-Lys-OH PA0 (11) Lys-Leu-Lys-Lys-OH PA0 (12) Lys-Asp-Leu-Lys-OH PA0 (13) Glu-Leu-Val-Ala-OH and PA0 (14) Leu-Pro-Ala-Gly-OH and acid addition salts thereof inhibit the proliferation of leukaemic cells and exhibit immunostimulant effect.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.