Phosphorylated glycosidase inhibitor prodrugs
US5043273A · kind A · utility
34Cited by
4References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 17, 1989 |
| Grant date | Aug 27, 1991 |
| Priority date | — |
| Expiry date | Aug 17, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/59
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method is provided for converting therapeutic glycosidase inhibitors to novel prodrugs by phosphorylation of a free hydroxyl group on the molecule to substantially reduce the glycosidase inhibitory activity without thereby substantially reducing the therapeutic activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.