Indolocarbazoles and the use thereof

US5043335A · kind A · utility

Assignee

• Godecke Aktiengesellschaft · DE

Inventors

• Jurgen Kleinschroth · Denzlingen, DE
• Johannes Hartenstein · Kirchzarten, DE
• Christoph Schachtele · Glückstadt, DE
• Claus Rudolph · Denzlingen, DE

Key dates

• Filing date: Jul 23, 1990
• Grant date: Aug 27, 1991
• Expiry date: Jul 23, 2010

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides 9,10,11,12-tetrahydro-9,12-epoxy-1H-diindolo [1,2,3-fg: 3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-1,3(2H)-dione and 9,10,11,12-tetrahydro-2-(tetrahydro-5-methoxy-2-furanyl) -9,12-epoxy-1H-diindolo[1,2,3-fg: 3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-1,3(2H)-dione process for the preparation thereof, pharmaceutical compositions containing the compounds, and use of the compounds in heart and blood vessel diseases such as thromboses, arterioscleroses, hypertension and inflammatory diseases, allergies, cancer and certain degenerative damage of the central nervous system, as well as diseases of the immune system.