Substituted 4-pyridone 3-carboxylic acid derivatives, method for their production and their pharmaceutical compositions
US5045549A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 6, 1987 |
| Grant date | Sep 3, 1991 |
| Priority date | — |
| Expiry date | Jul 6, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
New 4-Pyridone derivatives of General Formula are claimed ##STR1## in which R.sub.1 is methylamino,4-fluorophenyl, 2,4-difluorophenyl, R.sub.2 is hydrogen or a sulfur atom that is joined to the ring nitrogen by an ethylene bride, X is a hydrogen or a physiologically removable ester group and Y is a base of the general formula ##STR2## In formula IIa and IIb, R.sub.3 is hydrogen, lower alkyl, benzyl, formyl, acetonyl or a moiety of the formula ##STR3## Also claimed are the addition salts of compounds of formula I with pharmaceutically acceptable inorganic or organic acids or base and/or their hydrates. Also claimed are the methods of manufacture of compounds of formula I and their use as antibacterial agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.